- Knowledge of the incidence and geographic distribution of bladder cancer in dogs could facilitate identification of environmental hazards for people and their pets.
- Some breeds of dogs such as the Scottish Terrier have a risk of bladder cancer that is 18 times greater than other breeds, despite similar exposures.* This breed is useful therefore, to study the genetic determinants and mechanism of bladder cancer.
* Knapp DW, Glickman NW, DeNicola DB, Bonney PL, Lin TL, Glickman LT. Naturally-occurring canine transitional cell carcinoma of the urinary bladder: A relevant model of human invasive bladder cancer.
Urologic Oncology 5:47-59, 2000.